| 결핵약제에 의해 발생한 DRESS syndrome과 그 이후에 발생한
multiple drug hypersensitivity |
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| DRESS syndrome due to Anti-Tuberculous Drug |
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So Yeon Yoo, Jaechun Lee, Jong Hoo Lee, Mi Ok Kim |
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| Abstract |
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DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) is a potentially life threatening syndrome caused by exposure
to certain medications. That may cause skin rash, fever, inflammation of internal organs, lymphadenopathy, and characteristic
hematologic abdnormalities such ad eosinophilia, thrombocytopenia, and typical atypical lymphocytosis. The interval between the
starting of drug therapy and the onset of cutaneous reactions may be at least one month. Aromatic anticonvulsants
(phenytoin, phenobarbital, carbamazepine) and sulfonamides are the most common causes of DRESS. There has been only a
few case reports of DRESS syndrome induced by anti-tuberculous medication, Ethambutol, Rifampin, Isoniazid, Pyrazinamide. We
report a case of Ethambutol induced DRESS syndrome and multiple drug hypersensitivity to other antituberculosis drugs that
were used at after DRESS syndrome developed. |
| Key Words:
Drug Hypersenitivity Syndrome, ethambutol |
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