J Med Life Sci > Volume 11(1); 2014 > Article
Journal of Medicine and Life Science 2014;11(1):43-47.
DOI: https://doi.org/10.22730/jmls.2014.11.1.43    Published online December 18, 2018.
PCR 방법으로 진단된 위매독 환자 1예
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A Case of Gastric Syphilis Diagnosed by PCR Test: A Case Report
Jaemin Jo, Heung Up Kim, Sang Taek Heo
Correspondence:  Heung Up Kim,
Syphilis is chronic and systemic inflammation caused by T. pallidum infection. Because the diagnosis is exclusively depended on histology, its diagnosis could be very difficult in the patients without positive biopsy finding. We experienced a case of gastric syphilis diagnosed by polymerase chain reaction (PCR) in case of biopsy negative patients. So we report this simple method to diagnose gastric syphilis that failed to show spirochetes on histology. A 70 year-old man visited our hospital via private clinic with suspicious gastric malignancy finding on gastroscopy. Our gastroscopy showed the characteristic shape of multiple nodular erosions and ulcers of gastric syphilis. Warthin-Starry silver stain failed to find spirochetes. Repeated gastroscopy was done to take biopsy specimen for T. pallidum PCR and proved positive. We confirmed gastric syphilis and treated with intravenous antibiotics. After 4 months of treatment, all gastric lesions were disappeared.
Key Words: Syphilis, Gastric; Polymerase Chain Reaction; Diagnosis

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