HPV 백신의 효과와 안정성 |
김우진1, 김성엽2 |
1제주대학교 의과대학 의학과 2제주대학교 의과대학 산부인과학교실 |
The efficacy and safety of HPV vaccination |
Woo Jin Kim1, Sung Yob Kim2 |
1Department of Medicine, Cheju National University, Jeju 690-756, Korea 2Department of Obstetrics and Gynecology College of Medicine, Cheju National University, Jeju 690-756, Korea |
Correspondence:
Sung Yob Kim, Email: mdkim66@cheju.ac.kr |
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Abstract |
HPV vaccine was licensed for use in the United States and Europe in June 2006, and is now available in most nations. It was highly successful in reducing the incidence of precancerous cervical lesions caused by HPV-16 and HPV-18. The titer of HPV antibody was maintained during 4.5 years of the extended follow up phase. HPV prescreening before vaccination is generally not needed, because HPV vaccination has protective effect for the remaining types in infected women. Systemic clinical adverse events were reported by a similar proportion of vaccine and placebo recipients. The estimated rate of anaphylaxis following HPV vaccine is slightly higher than other vaccines. However, overall rates are very low and it may leave no serious sequelae if managed appropriately. The patient is required to be seen for about 15 minutes after vaccination. |
Key Words:
HPV vaccine, Gardasil, Cervarix |
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