J Med Life Sci > Volume 6(1); 2008 > Article
Journal of Medicine and Life Science 2008;6(1):13-20.
DOI: https://doi.org/10.22730/jmls.2008.6.1.13    Published online December 31, 2008.
자궁내막암에서의 방사선치료의 역할
노영호1, 김성엽2
1제주대학교 의과대학 의학과
2제주대학교 의과대학 산부인과학교실
The role of Adjuvant Radiation therapy in Endometrial carcinoma
Young Ho Roh1, Sung Yob Kim2
1Department of Medicine, Cheju National University, Jeju 690-756, Korea
2Department of Obstetrics and Gynecology College of Medicine, Cheju National University, Jeju 690-756, Korea
Correspondence:  Sung Yob Kim, Email: mdkim66@cheju.ac.kr
Abstract
Endometrial cancer is a third common gynecologic malignancy in Korea, affecting approximately 714 women per year. Despite the publication of several prospective randomized trials, there continues to be controversy regarding the use of adjuvant radiation therapy in endometrial cancer management. It is clear that most women with early stage, low-risk disease will do well without adjuvant therapy. Intermediate-risk patients are at risk for local regional relapse, and radiotherapy has been shown to effectively reduce this risk without significantly impacting overall survival. The absence of a clear impact on survival has resulted in a lack of consensus regarding the use of radiotherapy in intermediate-risk patients. At the same time, the patterns of failure in intermediate-risk patients have resulted in differing recommendations regarding appropriate radiotherapy targets. High-risk patients are also at risk for local failure, and targeted radiotherapy may be appropriate. In this article, we discuss the controversies surrounding the role of adjuvant radiotherapy in endometrial cancer using an evidence-based approach.
Key Words: Endometrial cancer, Adjuvant therapy, Radiation therapy


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