A rare case of idiopathic central precocious puberty in a 17-month-old girl |
Chae-Ho Kim, Kyung-Sue Shin |
Correspondence:
Kyung-Sue Shin, |
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Abstract |
Central precocious puberty (CPP) is defined as development of secondary sex characteristics in relation with activation
of the HPG axis before the age of 8 years in girls and before the age of 9 years in boys. CPP is far less common in
children before 3 years of age, particularly in females. Most girls with signs of puberty less than 3 years of age are
diagnosed with premature thelarche (PT). Although CPP presenting with early breast development should be differentiated
from PT, there is no diagnostic method which would definitely differentiate these two conditions. We present idiopathic
CPP before 3 years of age who presented with PT that rapidly progressed to CPP. Up to date, there are no predictive
clinical or laboratory tests that can identify the risk of progression to PP at time of onset. Therefore, all girls with PT
should be monitored clinically for accelerated pubertal progression. |
Key Words:
Precocious puberty; Premature thelarche; Premature pubarche |
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