J Med Life Sci > Volume 7(2); 2010 > Article
Journal of Medicine and Life Science 2010;7(2):13-17.
DOI: https://doi.org/10.22730/jmls.2010.7.2.13    Published online December 31, 2010.
고환피부염양 2기매독에 대한 임상-병리학적 고찰
제주대학교 의과대학전문대학원 피부과학교실
Clinico-pathologic Analysis of Scrotal Dermatitis-mimicking Secondary Syphilis
Jae-Wang Kim
Department of Dermatology, Jeju National University School of Medicine, Jeju, Korea
Correspondence:  Jae-Wang Kim, Email: rulid@jejunu.ac.kr
Secondary syphilis may represent as a variety of mucocutaneous lesions, which has led to its reputation as the "great imitator or great impersonator". There have been few published case reports of secondary syphilis masquerading as scrotal dermatitis in Western countries. Herein, we retrospectively analyzed the clinico-histopathological data of 11 cases of secondary syphilis mainly invading the scrotum. Mean age was 62.6 years old. The most common initial presumptive diagnosis was scrotal eczema(36.4%). ln 81.8%, there were skin lesions in another sites besides scrotum. 63.6% of the presented patients could memorize the antecedent episode of primary syphilis(hard chancre). The most common histopathologic findings(90.9%) were perivascular plasmacytoid infiltrates with endothelial swellings. Conclusively, we should maintain a high index of suspicion for secondary syphilis because this disease can present in many ways, including an eczematoid scrotal en ption.
Key Words: Scrotum; Dermalitis; secondary syphilis
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