J Med Life Sci > Volume 7(2); 2010 > Article
Journal of Medicine and Life Science 2010;7(2):1-6.
DOI: https://doi.org/10.22730/jmls.2010.7.2.1    Published online December 31, 2010.
남성 발기부전의 임상적 진단과 치료에 대한 접근
김영주, 김성대
제주대학교 의학전문대학원 비뇨기과학교실
Approach to clinical diagnosis and treatment of erectile dysfunction of man
Young-Joo Kim, Sung Dae Kim
Department of Urology, Jeju National University School of Medicine, Jeju, Korea
Correspondence:  Sung Dae Kim, Email: mecksd@jejunu.ac.kr
Abstract
The sexual dysfunction of man is mainly divided into four parts as erectile dysfunction, sexual desire disorder. premature ejaculation and orgasmic disorder. Above of all things, erectile dysfunction is the most important and common disease of these. The past, it is regard to ereclile dysfunction of man is natural event according to aging and little effort to improve or treat about it. But as the molecular biology and pharmacology become more and more advanced, it comes from biological factor and is possible to overcome. The preference of therapeutic option in patients of erectile dysfunction is various but becomes less invasive therapy. The phosphodiesterase type-5 inhibitors (PDE5-ls) sildenafil, vardenafil, tadalafil, urodenafil and mirodenafil are widely used as IirsHine therapy for erecli1e dysfunction (ED). Since the approval of sildenafil in 1998, more than 40 million men worldwide have been successfully treated with PDE5-ls. Pharmacologically, the proven safely and high tolerance of PDE5-ls is an attractive tool to investigate further physiological functions of PDE5, for example the modulation of intracellular cyclic GMP (cGMP) pools. The aim of review is to summarize clinical knowledge and practical approach about erectile dysfunction of man and to share with non-urologist in these information. Therefore, we recommend that even though non-urologist, it is worthy to know of this review.
Key Words: erectile dysfunction; diagnosis; treatment


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