J Med Life Sci > Volume 7(1); 2010 > Article
Journal of Medicine and Life Science 2010;7(1):161-164.
DOI: https://doi.org/10.22730/jmls.2010.7.1.161    Published online June 30, 2010.
사지마비가 통반된 Enterovirus 71 급성 뇌수막 뇌염 1례
오민수1, 이진숙2, 김언주3, 홍정연2
A case with enterovirus 71 acute meningoencephalitis associated with quadriplegia
Min Soo Oh1, Jin Sook Lee2, Yun Ju Kim3, Jung Yun Hong2
1Jeju National University School of Medicine, Jeju, Korea
2Department of Pediatrics, Jeju National University School of Medicine, Jeju, Korea
3Division of Microbiology, Department of public Health Research, Institute of Environmental Research of Jeju Special self-Governing Province, Jeju, Korea
Correspondence:  Jung Yun Hong, Email: hongped@jeunu.ac.kr
Since 1997, epidemic of hand-foot-mouth disease caused by Enterovirus 71has become an important issue in the AsiaPacific region because some patients progress to severe neurological complication such as acute flaccid paralysis, brainstem encephalitis. The authors experienced and report that an 12-month-old boy with hand-foot-mouth disease developed acute meningoencephalitis associated with quadriplesia. Enterovirus 71 was isolated in CSF and stool by RT-PCR and sequencing, but MRI showed no lesion in brain and spinal cord. Although IVIG treatment was not shown effective, the patient recovered fully by supportive treatment.
Key Words: Enterovirus 71; Menigoencephalitis; Brainstem encephalitis; Quadriplesia
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