Effect of Orostachys iwarenge Hara on the proliferation of dermal papilla ceIls

Kang, Jung-Il; Kim, Sang-Cheol; Hyun, Jae-Hee; Boo, Hye-Jin; Hong, Ji-Young; Yoo, Eun-Sook; Kang, Hee-kyoung

doi:2010.7.1.139

J Med Life Sci > Volume 7(1); 2010 > Article

Journal of Medicine and Life Science 2010;7(1):139-142.
DOI: https://doi.org/10.22730/jmls.2010.7.1.139 Published online June 30, 2010.

연화바위솔의 모유두 세포 증식 효능

강정일, 김상철, 현재희, 부혜진, 홍지영, 유은숙, 강희경

제주대학교 의학전문대학원 약리학교실

Effect of Orostachys iwarenge Hara on the proliferation of dermal papilla ceIls

Jung-Il Kang, Sang-Cheol Kim, Jae-Hee Hyun, Hye-Jin Boo, Ji-Young Hong, Eun-Sook Yoo, Hee-kyoung Kang

Department of Pharmacology, Jeju National University School of Medicine, Jeju, Korea

Correspondence: Hee-kyoung Kang, Email: pharmkhk@jejunu.ac.kr

Abstract

In this study, we investigated the hair-growth effect ofplants growing in Jeju by the proliferation of dermal papilla cells. Dermal papilla cells are specialized mesenchymal cells that located at the bulb region of hair follicles. The cells play crucial roles in hair formation, growth, and cycling. When immortalized vibrissa dermal papilla cells were treated with several extracts, the extract of Orostachys iwarenge Hara increased proliferation of immortalized vibrissa dermal papilla cells. These results suggest that O. iwarenge extract has the potential to promote hair growth via the proliferation of dermal papilla.

Key Words: Hair growth; Orostachys iwarenge; Hara; Dermal papilla cells