전립선암 치료의 최신지견 |
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Update of treatment for Prostatic cancer |
Kyung Kgi Park, Sung Dae Kim, Young-Joo Kim, Jung-Sik Huh |
Correspondence:
Jung-Sik Huh, |
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Abstract |
Prostate cancer is a major public health problem in South Korea. Various effective treatments have been introduced to the
various types of literature. We will summarize the reasonable and applicable suggestions for appropriately selecting treatments
for prostate cancer. We suggest suitable management plan based on recurrence risk. At very low risk group, active surveillance
is applicable to minimize treatment complications. At low risk group, active surveillance is applicable to patients with a life
expectancy of less than 10 years, however, patients who have greater than 10 years of life expectancy need radical therapy
with either surgery or radiation. At moderate risk group, active surveillance, short term neoadjuvant hormone and radiation
therapy are suitable at less than 10 years of life expectancy. At high risk group, concomitant radiation therapy and long term
adjuvant therapy or radical surgery or brachytherapy are applicable to the patients. At very high risk groups, concomitant
hormone and radiation therapy or hormone therapy only are suggested. In patients with distant metastasis, mainly, hormone
therapy is preceded. At castration refractory stage, Docetaxel based chemotherapy is recommended. If meaningful regression
for prostate cancer progression is not inspected, treatment plan does just focused on patient symptom control rather than
survival extension. To conclude, suggested treatment options should be suggested based on their stage, general condition and
life expectancy. |
Key Words:
Prosate cancer, Chemotherapy, Hormonal therapy |
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