J Med Life Sci > Volume 10(1); 2013 > Article
Journal of Medicine and Life Science 2013;10(1):66-70.
DOI: https://doi.org/10.22730/jmls.2013.10.1.66    Published online December 18, 2018.
전립선암 치료의 최신지견
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Update of treatment for Prostatic cancer
Kyung Kgi Park, Sung Dae Kim, Young-Joo Kim, Jung-Sik Huh
Correspondence:  Jung-Sik Huh,
Abstract
Prostate cancer is a major public health problem in South Korea. Various effective treatments have been introduced to the various types of literature. We will summarize the reasonable and applicable suggestions for appropriately selecting treatments for prostate cancer. We suggest suitable management plan based on recurrence risk. At very low risk group, active surveillance is applicable to minimize treatment complications. At low risk group, active surveillance is applicable to patients with a life expectancy of less than 10 years, however, patients who have greater than 10 years of life expectancy need radical therapy with either surgery or radiation. At moderate risk group, active surveillance, short term neoadjuvant hormone and radiation therapy are suitable at less than 10 years of life expectancy. At high risk group, concomitant radiation therapy and long term adjuvant therapy or radical surgery or brachytherapy are applicable to the patients. At very high risk groups, concomitant hormone and radiation therapy or hormone therapy only are suggested. In patients with distant metastasis, mainly, hormone therapy is preceded. At castration refractory stage, Docetaxel based chemotherapy is recommended. If meaningful regression for prostate cancer progression is not inspected, treatment plan does just focused on patient symptom control rather than survival extension. To conclude, suggested treatment options should be suggested based on their stage, general condition and life expectancy.
Key Words: Prosate cancer, Chemotherapy, Hormonal therapy


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