| 말기 심부전 환자를 위한 외과적 치료의 최신경향 |
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이석재 |
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제주대학교 의학전문대학원 흉부외과학교실 |
| Current trend of surgical management for end-stage heart disease |
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Seogjae Lee |
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Department of Thoracic and cardiovascular Surgery, Jeju National University Scool of Medicine, Jeiu, Korea |
Correspondence:
Seogjae Lee, Email: sj1106@jejunu.ac.kr
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| Abstract |
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The prevalence of heart failure is increasing，and the prognosis of end-stage heart failure remains dismal. The gold-standard therapy in end-stage heart failure remains cardiac transplantation at the present time ，but there is a great excess of eligible candidates compared with the number of donor organs. Advances in mechanical support， the development of the left ventricular assist device (LVAD)，and the total artificial heart has reduced mortality and morbidity in patients awaiting transplantation，and LVADs are now approved as a strategy for destination therapy. Minialurlzalion， increased device durability，and complete implantabilily may render LVADs an option in earlier stages of heart failure，as a bridge to myocardial recovery or even as a viable alternative to Transplantation. Alternative strategies under investigation are cell therapy and xeno-transplantation. ln the present article，current and potential future therapeutic options ln end-stage heart failure are reviewed. |
| Key Words:
End-stage heart disease, Mechanical support, Left ventricular assist device |
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