| Subcutaneous Mycetoma of Pseudallescheria boydii complexes
Revealed by 18S rDNA sequencing |
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Ji Eun Park, Young Ree Kim, Sung Ha Kang, Sun Hyung Kim, Jae-Wang Kim, Keun Hwa Lee |
Correspondence:
Young Ree Kim,
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| Abstract |
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Pseudallescheria ellipsoidea, one of the P. boydii complexes, is a ubiquitously isolated saprophytic fungus from soil, poultry,
cattle, sewage, and polluted water. It is known to cause various diseases such as subcutaneous mycetoma in immunocompetent
individuals and sepsis in immunocompromized patients. We experienced a case of cutaneous P. ellipsoidea infection in a 79-
year-old man. He was taking medication for diabetes mellitus and heart disease and visited our dermatologic outpatient clinic
with violet-colored, nontender, fluctuating, keratotic, conglomerated plaques on the right forearm. Skin biopsy was consistent
with foreign body reaction to ruptured epidermal cyst. After skin culture, PCR and sequencing revealed P. boydii complexes,
with forward sequencing showing 96% homology of P. boydii, and revere sequencing showing homology 100% of P. ellipsoidea.
After the patient received fluconazole for 5 weeks, discharged with improved conditions. |
| Key Words:
Pseudallescheria boydii complexes, Mycetoma, Sequencing |
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