Effect of <i>Hizkia fusiforme</i> Okamura on the proliferation of dermal papilla celIs

Kang, Jung-Il; Kim, Sang-Cheol; Kim, Min-Kyoung; Boo, Hye-Jin; Kim, Eun-Ji; Jeon, You-Jin; Yoo, Eun-Sook; Kang, Hee-Kyoung

doi:2011.8.1.16

J Med Life Sci > Volume 8(1); 2011 > Article

Journal of Medicine and Life Science 2011;8(1):16-20.
DOI: https://doi.org/10.22730/jmls.2011.8.1.16 Published online December 30, 2011.

톳의 모유두 세포 증식 효능

강정일¹, 김상철¹, 김민경¹, 부혜진¹, 김은지¹, 전유진², 유은숙¹, 강희경¹

¹제주대학교 의학전문대학원 약리학교실
²아쿠아그린텍(주)

Effect of Hizkia fusiforme Okamura on the proliferation of dermal papilla celIs

Jung-Il Kang¹, Sang-Cheol Kim¹, Min-Kyoung Kim¹, Hye-Jin Boo¹, Eun-Ji Kim¹, You-Jin Jeon², Eun-Sook Yoo¹, Hee-Kyoung Kang¹

¹Department of pharmacology, Jeju National University School of medicine, Jeju of Korea
²Aqua Green Technology Co., Ltd., Jeju-do, Republic of Korea

Correspondence: Hee-Kyoung Kang, Email: pharmkhk@jejunu.ac.kr

Abstract

This study was conducted to evaluate the hair-growth effects of seaweeds in Jeju by the proliferation of dermal papilla cells. Dermal papilla cells are mesenchymally-derived cells which play a pivotal role in the morphogenesis, regeneration, and growth of hair. Immortalized vibrissa dermal papilla cells were treated with algae extracts such as extract of Hizkia fusiform Okamura, extract of Padina arborescens Holmes, extract of Sargassum thunbergil, extract of Gelidium amansii, and extract of Grateloupia turuturu Yamada. Among them, the extract of H. fusiforme significantly increased proliferation of immortalized vibrissa dermal papilla cells. The results suggest that H. fusiforme extract has the potentiat to promote hair growth via the proliferation of dermal papilla cells.

Key Words: hair growth; Hizkia fusiforme Okamura; dermal papilla cells