| 만성질환에 의한 빈혈 |
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김우건 |
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제주대학교 의학전문대학원 내과학교실 |
| A short review of Anemia of chronic disease: clinical feature, mechanism and the treatment |
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Wookun Kim |
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Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea |
Correspondence:
Wookun Kim, Email: mwkkim@naver.com
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| Abstract |
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Anemia of chronic disease is the second common anemia following the iron deficiency anemia. it has been known to be associated with acute or chronic infection, however, it is now known to be from any disease with inflammation including cancer This anemia is usually normocytic and normochromic and the degree of anemia is not severe. The poor utilization of iron into erythropoiesis due to entrapment of iron in macrophages and reticuto-endothelial cells has been considered as the main mechanism of developing this anemia. However ， it is recognized that various cytokines take the significant roles in the pathogenesis. Although erythropoietin has been shown to have some efficacy in certain situations such as in anemia from cancer ，The knowledges of its adverse effect in cancer prognosis，away from original expectation ，is being accumulated recently. |
| Key Words:
Anemia of chronic disease, hepcidin，Erythropoietin |
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