J Med Life Sci > Volume 2(2); 2004 > Article
Journal of Medicine and Life Science 2004;2(2):71-77.
DOI: https://doi.org/10.22730/jmls.2004.2.2.71    Published online December 31, 2004.
골격근을 이용한 흰쥐 심장성형 후 심장을 지배하는 중추신경로에 관한 연구
변경희, 고선영, 김재우, 이봉희
제주대학교 의과대학 해부학교실 및 제주대학교 의과학연구소
CNS innervation to the heart after skeletal muscle transplantation in the rat
Kyung-Hee Byun, Sun-Young Ko, Jae-Woo Kim, Bong-Hee Lee
Department of Anatomy and Neurobiology, Institute of Medical Science, Cheju National University College of Medicine, Jeju 690-756, Korea
Correspondence:  Bong-Hee Lee, Email: bhleel@cheju.ac.kr
The congestive heart failure is known as one of the most popular cause of human death. The purpose of this study were to identify the CNS pathway innervating heart after reconstruction using latissimus dorsi muscle by using the pseudorabies virus injection into the hippocampus after entorhinal cortex lesions. The pseudorabies virus labelled neurons were distributed at several different nuclei including paraventricular nucleus. No significant morphological changes were observed in the CNS heart innervation after reconstruction. These data suggested that the CNS innervation showed no morphological changes throughout the whole brain areas after heart reconstruction.
Key Words: Heart, CNS pathway, pseudorabies virus
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