J Med Life Sci > Volume 15(2); 2018 > Article
Journal of Medicine and Life Science 2018;15(2):42-45.
DOI: https://doi.org/10.22730/jmls.2018.15.2.42    Published online January 3, 2019.
대장암 동물 모델에 대한 이해
Understanding animal models on colorectal cancer
DoYoung Lim
Mayo Clinic
Correspondence:  DoYoung Lim, Email: ldydo@daum.net
Colorectal cancer (CRC) is a third leading cause of cancer-related death in cancer patients. Sporadic and inflammation-related colon carcinogenesis are major mechanism of colorectal cancer. In vivo CRC models have been developed and implicated to understand their mechanisms upon a different type of CRC. Moreover, recently animal models have played important roles in chemopreventive and preclinical trials over the years. In this mini-review, the aim is to introduce various animal models of CRC and help the understanding to establish in vivo experimental plans according to the cancer type of CRC.
Key Words: Colorectal, cancer, Animal, model, Sporadic
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