Bilateral striopallidodentate calcinosis in a patient with myasthenia gravis

Shin, Ji-Yong; Kang, Sa-Yoon

doi:2015.12.2.37

J Med Life Sci > Volume 12(2); 2015 > Article

Case Report

Journal of Medicine and Life Science 2015;12(2):37-38.
DOI: https://doi.org/10.22730/jmls.2015.12.2.37 Published online December 18, 2018.

Bilateral striopallidodentate calcinosis in a patient with myasthenia gravis

Ji-Yong Shin, Sa-Yoon Kang

Correspondence: Sa-Yoon Kang,

Abstract

Bilateral symmetric calcification involing striatum, pallidum with or without deposit in dentate nucleus is reported from asymptomatic individuals to a variety of neurological conditions. Clinically it may present with an array of movement disorders, dementia, cerebellar impairment and speech disorder. We report a myasthenia gravis patient with dysarthria which did not respond to pyridostigmin. Brain MRI showed bilateral striopallidodentate calcinosis (BSPDC). To our knowledge, there is no reported case having anti-acetylcholine receptor antibody and massive intracranial calcifications. This case indicates that BSPDC may develop in diverse neurological disorders.

Key Words: Anti-acetylcholine Receptor Antibody, Calcification, Myasthenia Gravis, MRI