| 부당경량아로 출생한 사춘기 이전의 저신장 소아에서 인성장호르몬의 치료 효과 |
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| The Efficacy of Recombinant Human Growth Hormone Treatment in Prepubertal Children
with Short Stature due to Small for Gestational Age |
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Kyung-Sue Shin |
Correspondence:
Kyung-Sue Shin,
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| Abstract |
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Recombinant human growth hormone (GH) has been recognized as an effective treatment for short-statured children born
small for their gestational age (SGA). This report described the treatment of recombinant human GH in prepubertal children with
short stature due to SGA. Recombinant human GH was administered with a subcutaneous dose of 0.1 IU/kg/day(0.033
mg/kg/day) for 6 days per week. Height velocity and height standard deviationscore (SDS) were increased, and recombinant
human GH was well tolerated and relatively safe. However, despite similar circumstance, there were some differences between
two cases with a gained height velocity and height SDS. Although the response to GH treatment is influenced by the dose, age
at start, stature at start, and means parental height, further studies are necessary to predict the efficacy of GH treatment in
short-statured children born small for SGA. |
| Key Words:
Human Growth Hormone, Small for Gestational Age |
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